MeSsy with Christina Applegate & Jamie Lynn Sigler
On this podcast, Christina Applegate and Jamie Lynn Sigler get vulnerable about the curveballs that life can throw…theirs just happens to be MS. Join them each week as they self-reflect, learn, laugh, and grow through their own raw and often-times hilarious conversations with each other, friends, co-stars, and the people that keep them going through the messiness of life.
Latest Episode
This Is Not Your Fault (06.01.2026)
Previous Episodes
- There’s a Lot of Unknown in Life
- Are You Mad At Me? with Meg Josephson
- Montel Williams
- We're All Crushing It
- How to Feel Safe in Your Body with Deb Dana (Re-Release)
- You Don’t Deserve to Feel Guilt
- Best of MeSsy: Edie Falco, Jean Smart, and Katey Sagal
- Robert Iler
- How Vulnerable Can I Be? with Craig Thomas
- We Don’t Move Past It, We Move With It
- Everybody’s Got Something
- It’s Okay to Be Yourself with Baylen Dupree
- Megan Mullally
- Do What You Can When You Can
- Fraser Olender
- We Are Not the Things That Happen to Us
- Change Your Brain, Change Your Pain with Dr. Daniel Amen
- We Have to Pivot
- I Just Wanna Be Stoned
- Ed Helms
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